tyrosinase inhibition and antioxidant properties in germany
Tyrosinase inhibition and antioxidant properties
Tyrosinase inhibition. With the increasing of the inhibitor concentration, the values of both K m and V max are reduced, while the ratio K m /V max remains quite the same. The slopes are independent from the concentration of FEE, which indicates that the compound is an uncompetitive inhibitor of the enzyme.
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Tyrosinase enzyme inhibition . Tyrosinase is a cupper-containing enzyme mostly found in animals and plants. Also, it is responsible for enzymatic browning reactions in damaged fruits. Therefore, investigations about discovering new tyrosinase inhibitors are increasing for using in foods and cosmetics . This method is based on the measurement of the absorbance of dopachrome as a result of the reaction between L-tyrosine and L-DOPA.
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Inhibition of cellular tyrosinase activity and melanin production was also investigated in melanoma B16F10. cells. Antioxidant activity, total phenolic and flavonoids contents were determined using standard in vitro methods. HPLC-DAD-MS was used to identify phenolic profile of the active extract.
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Evaluation of Anti-Tyrosinase and Antioxidant Properties of Four Fern Species for Potential Cosmetic Applications Adrià Farràs 1,2, Guillermo Cásedas 1, Francisco Les 1,3, Eva María Terrado 1, Montserrat Mitjans 2 and Víctor López 1,3,* 1 Department of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, 50830 Villanueva de
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Thus, there has been considerable interest in tyrosinase inhibitors in the food industry and the needs for natural tyrosinase inhibitors have gradually been increased because safety is strictly monitored in the food industry. Many studies have suggested the antioxidant properties of different mushrooms [21, 22]. These studies have generally used mushroom extracts; little attention has been paid to demonstrating the antioxidant activities or antityrosinase activity of mycelium culture ...
Send InquiryAntioxidant activity, acetylcholinesterase and tyrosinase
The highest inhibition value was obtained for the C. umbellatum ethanolic extract (94.24% – AChE inhibition and 74.39% – tyrosinase inhibition) and the highest content of flavones 496.28 ± 8.91 μg RE/mL was also determined in the same extract. The highest inhibition of the ethanolic extract could be due to the presence of high contents of flavone.
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Correlation studies between polyphenol content and antioxidant activity (A) and between polyphenol content and tyrosinase inhibition (B). Pearson r values confirm that there is a correlation between polyphenol content and antioxidant activity measured by the ORAC method, whereas no correlation exists between polyphenol content and the inhibition of the tyrosinase enzyme.
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Tyrosinase Inhibitory Effects and Antioxidant Properties of Paeonol and Its Analogues Tian-Hua zHu, Yan-Ying yu * and Shu-Wen cao Department of Chemistry, Nanchang University, Nanchang 330031, PR China. Received December 19, 2012; Accepted March 4, 2013
Send InquiryInhibition of melanogenesis and antioxidant properties
The purpose of the study was to investigate the antimelanogenic and antioxidant properties of Magnolia grandiflora L. flower extract. In the study, the inhibitory effects of M. grandiflora L. flower extract on mushroom tyrosinase, B16F10 intracellular tyrosinase activity and melanin content were determined spectrophotometrically. Meanwhile, the antioxidative capacity of the flower extract was also investigated.
Send InquiryAntibacterial, antioxidant and tyrosinase-inhibition
Tyrosinase inhibition property. Tyrosinase inhibition activity was determined as described by Momtaz et al. , with L-3,4-dihydroxyphenylalanine (L-DOPA, Sigma) and tyrosine as substrates. Samples were dissolved in dimethyl sulfoxide (DMSO) to a concentration of 20 mg/ml, and further diluted in potassium phosphate buffer (50 mM, pH 6.5) to 600 μg/ml. Assays were carried out in a 96-well micro-titre plate and a Multiskan FC plate reader (Thermo scientific technologies, China) was used.
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Inhibition of cellular tyrosinase activity and melanin production was also investigated in melanomaHowever, currently available tyrosinase inhibitors suffer from toxicity and/or a lack of efficacy andHPLC-grade acetonitrile was obtained from Merck KgaA (Darmstadt, Germany) and formic acid was
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Percent inhibition of tyrosinase activity was determined according to the formula: inhibition.Thus, the EECiMs that were determined to have antioxidant activities and a tyrosinase inhibitory property in our study can be used as additives in natural antioxidants and functional cosmetics.
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Antibacterial, antioxidant and tyrosinase-inhibition activities of pomegranate fruit peel methanolic extract Olaniyi A Fawole1, Nokwanda P Makunga2 and6. Hazra B, Sarkar R, Biswas S, Mandal N: Comparative study of the antioxidant and reactive oxygen species scavenging properties in the
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In this work, the antioxidant and tyrosinase inhibitory activities of hydrophilic and lipophilic extracts, together with total polyphenol content, wereL-DOPA and tyrosinase were solved in buffer. The inhibition of tyrosinase was determined at 475 nm. Methanolic extracts were dissolved in methanol
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Antioxidant and tyrosinase inhibition activity of the fertile fronds and rhizomes of three different Drynaria species. Joash Ban Lee Tan.Methods: This study evaluates the antioxidant properties of the methanolic extracts of the fertile fronds and rhi-zomes from three species in this genus: Drynaria
Send InquirySynergistic Promotion on Tyrosinase Inhibition by Antioxidants.
The inhibitory effects of the four compounds and their mixtures on tyrosinase were evaluated. l-Tyrosine or 3-(3,4-dihydroxyphenyl)-l-alanine (l-DOPA)The two agents had a synergistic inhibitory effect on tyrosinase activity. These results provided a novel synergistic strategy for antioxidants and
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Antioxidant and tyrosinase inhibition properties of leaves and rhizomes of ginger species. Food Chem.The Anticancer, Antioxidant and Antimicrobial Properties of the Sesquiterpene β-Caryophyllene from the Essential Oil of Aquilaria crassna.
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Products referenced in Antioxidant activities and tyrosinase inhibition effects of Phaleria macrocarpa extracts.The ethyl acetate and chloroform extracts of stems, leaves and fruits of Phaleria macrocarpa were screened for their antioxidant capacity and tyrosinase inhibition properties.
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Keywords Ascophyllum nodosum -antioxidant activity-antimicrobial activity-tyrosinase inhibition.tyrosinase activity at the IC50 value of 0.1 mg mL−1. The outcomes of our study support potential.tion of their antioxidant properties (Funahashi et al.
Send InquiryTyrosinase Inhibitory Effects and Antioxidant Properties of Paeonol
These paeonol analogues had suggested remarkable inhibition toward tyrosinase. Among them, paeonol (a) exhibited the strongest inhibition activity (IC50 =0.21 mM) as well as showed potent scavenging activity on the DPPH radical. The inhibition kinetics revealed that paeonol (a) was a
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