traditional toxicity study of a rubber antioxidant, 2 in germany
Toxicological Evaluation of the Methanol Extract
The present study was designed to evaluate acute and repeated dose toxicity of the methanol extract (ME) of the Gmelina arborea stem bark. Materials and Methods: For the acute toxicity study, ME of G. arborea was orally administered to Swiss albino mice at a dose range of 300–5000 mg/kg.
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Methods 2, Ultrasound and Traditional Solvent Extraction
CO2, Ultrasound and Traditional Solvent Extraction ... toxicity and deterioration 2. Antioxidant can ... Germany). After 3 min of incubation, 2 mL of 7.5 % sodium carbonate solution was
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Phytochemical, Antimicrobial, and Toxicological Evaluation
2.5. Toxicity of Extracts to Human Erythrocytes. The cellular toxicity of the extracts from different plants was determined . Erythrocytes were isolated from human blood by removing plasma and buffy coat and suspended in phosphate buffered saline (10 mM phosphate, 150 mM sodium chloride) making a final concentration of 2% erythrocytes.
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Antioxidant and Toxicity Studies of 50% Methanolic Extract
In subchronic toxicity study, there were no observable changes in the general behaviour of all the treated rats (groups 1, 2, and 3) as compared to the control group. No significant changes were detected in either the bodyweights (Figure 4 ) or relative organ weights (Table 1 ) of all the treated rats.
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Metabolic dephenylation of the rubber antioxidant N
N-Phenyl-2-naphthylamine (P2NA) was widely used as oxidation inhibitor, particularly in rubber manufacturing. Technical-grade P2NA was con Investigations in humans and mammalian species revealed that small amounts of 2NA are excreted into urine after exposure to P2NA.
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Study of Hypoglycemic, Hypocholesterolemic and Antioxidant
The results of this study indicate that Mentha spicata as a species with high antioxidant activity reduces blood glocuse levels in diabetic rats with alloxan (150 mg/kg). The leaf aqueous extract of Mentha spicata plant caused a significnt (p˂0.001) reduction in blood glocuse levels ( Table 2 ).
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Research Article Antioxidant and Toxicity Studies of 50%
Research Article Antioxidant and Toxicity Studies of 50% Methanolic Extract ... e present study evaluated the antioxidant activity and potential toxicity of % methanolic extract of Orthosiphon stamineus ... ders [ ]. e bene ts of the traditional use of Orthosiphon stamineus have also been supported by the isolation and
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Drug-Induced Liver Toxicity and Prevention by Herbal
Herbal antioxidants have attracted the researchers due to its potential and efficacy against drug-induced liver toxicity. Natural products used in China and India as traditional medicine for the treatment of liver disorders are of great interest in these days.
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Comparative study of antidiabetic activity of Cajanus
Antioxidant study and quantification of phenolic compound of both the extracts revealed that they have high antioxidant capacity. ... Acute toxicity test . Acute toxicity study was performed for the extract according to the acute toxic ... of fasting blood glucose level during the 2-h study period. Within 30 min of administration of glucose ...
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In vitro characterization and in vivo toxicity
Organic acid and antioxidant profiles of Xeniji fermented foods were evaluated. Moreover, oral acute (5 g/kg body weight) and subchronic toxicity (0.1, 1 and 2 g/kg body weight) of Xeniji were tested on mice for 14 days and 30 days, respectively. Mortality, changes of body weight, organ weight and serum liver enzyme level were measured.
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Toxicity study of a rubber antioxidant
The chemical structure of 2-mercaptobenzimidazole (2-MBI), which is widely used as a rubber antioxidant, is partially similar to those of thioureaIn order to determine the oral toxicity of 2-MBI, a 28-day repeated dose toxicity study in Wistar rats followed by observation over a 14-day recovery
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Thyrotoxic rubber antioxidants, 2-mercaptobenzimidazole and its methyl derivatives, cause both inhibition and induction of drug-metabolizing activity inThis present study provides direct evidence at a molecular level to show that exposure to MBI could induce changes in the structure and function of
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Comparative toxicokinetic/toxicodynamic study of rubber
2-Mercaptobenzimidazole (MBI), a rubber antioxidant, is known to exhibit potent thyroid toxicity in rats, whereas its methylated derivatives areTo characterize this methyl-substituent effect on the thyroid toxicity of MBI, comparative toxicokinetic analyses have been conducted in the present study.
Send InquiryAntioxidant and Toxicity Studies of 50% Methanolic Extract
The present study evaluated the antioxidant activity and potential toxicity of 50% methanolic extract of Orthosiphon stamineus (Lamiaceae) leaves (MEOS) after acute and subchronic administration in rats. Superoxide radical scavenging, hydroxyl radical scavenging, and ferrous ion chelating methods
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Antimicrobial, antioxidant, toxicity and phytochemical assessment
Antioxidant activity was assessed using the 2,2-diphenyl-1-picryl-hydrazyl assay and phytochemical screening was carried out using standard procedures.The leaves of A. uliginosa were collected in September 2012 from the airport garden of Cotonou, department of Littoral, Southern Benin.
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A study of antioxidant activity, enzymatic inhibition : Internet Archive
This study evaluated ethanolic and aqueous extracts of selected Sudanese plants that are traditionally used to treat diabetes.All plant extracts with exception of Acacia senegal revealed significant antioxidant activity in DPPH free radical scavenging assay.
Send InquiryPhytochemical, Toxicity, Antimicrobial and antioxidant Screening
The study of antioxidant chemistry is on the increase in recent times because oxidation reactions can produce excess free radicals which can start chain reactions thatThe extracts were collected and concentrated with the aid of a Bucchi rotavapor and stored in a desiccator prior to further analysis.
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Endogenous Antioxidants: A Review of their Role in | IntechOpen
All these antioxidant systems have very important role in preserving the oxide/reduction equilibrium in the cell. To understand the role of the transcription factor Nrf2 in regulating the processes of antioxidant defense, it must also know the role of many of the endogenous antioxidants that occur
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Toxicity of halloysite clay nanotubes in vivo : a Caenorhabditis elegans
Here we investigated the toxicity of halloysite clay nanotubes in vivo employing a Caenorhabditis elegans nematode as a model organism. Using enhanced dark-field microscopy and physiological tests, we found that halloysite is localised exclusively in the alimentary system and does not induce severe
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Antioxidant Activity and Cytotoxicity of Rang Chuet (Thunbergia)
Results from this study will provide a better understanding of the antioxidant properties and cytotoxicity of this plant and possibly lead to the identification of plants with high antioxidant activity for further investigation and development into value-added food products and neutraceuticals.
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